Gene editing technology for treatment-resistant cancer could be a ‘scientific layup’ to treat other diseases
For the first time, a new #gene editing technology called base editing was used to modify immune cells and successfully treat a teen with treatment-resistant #leukemia. A month afterward, 13-year-old Alyssa was in remission, and she continues to do well several months later.
The treatment is a modification of chimeric antigen receptor, or CAR, T-cell therapy. But instead of using the #CRISPR gene editing technique to modify the patient’s immune cells, the clinicians used the more precise base editing technique to alter donor immune cells.
Those edited cells are given to the patient to “rapidly find and destroy T-cells in the body, including leukemic T-cells,” according to a news release from University College London.#geneediting #cancertreatment